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Acetylation Mimics Within a Single Nucleosome Alter Local DNA Accessibility In Compacted Nucleosome Arrays

The activation of a silent gene locus is thought to involve pioneering transcription factors that initiate changes in the local chromatin structure to increase promoter accessibility and binding of downstream effectors. To better understand the molecular requirements for the first steps of locus act...

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Detalles Bibliográficos
Autores principales: Mishra, Laxmi N., Pepenella, Sharon, Rogge, Ryan, Hansen, Jeffrey C., Hayes, Jeffrey J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052607/
https://www.ncbi.nlm.nih.gov/pubmed/27708426
http://dx.doi.org/10.1038/srep34808