Cargando…

Role of areca nut induced JNK/ATF2/Jun axis in the activation of TGF-β pathway in precancerous Oral Submucous Fibrosis

Oral submucous fibrosis (OSF) is potentially premalignant with progressive and irreversible extracellular matrix deposition accompanied by epithelial atrophy and like other fibrotic disorders, is primarily a TGF-β driven disease. OSF is caused by prolonged chewing of areca nut. Our previous studies...

Descripción completa

Detalles Bibliográficos
Autores principales:	Pant, Ila, Rao, S. Girish, Kondaiah, Paturu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052620/ https://www.ncbi.nlm.nih.gov/pubmed/27708346 http://dx.doi.org/10.1038/srep34314

Ejemplares similares

Role of Areca Nut Induced TGF-β and Epithelial-Mesenchymal Interaction in the Pathogenesis of Oral Submucous Fibrosis
por: Pant, Ila, et al.
Publicado: (2015)

Activation of TGF-β Pathway by Areca Nut Constituents: A Possible Cause of Oral Submucous Fibrosis
por: Khan, Imran, et al.
Publicado: (2012)

Epithelial atrophy in oral submucous fibrosis is mediated by copper (II) and arecoline of areca nut
por: Khan, Imran, et al.
Publicado: (2015)

Areca nut and its role in oral submucous fibrosis
por: Prabhu, Rachana V., et al.
Publicado: (2014)

Characterization of a Novel Dermal Fibrosis Model Induced by Areca Nut Extract that Mimics Oral Submucous Fibrosis
por: Chiang, Min-Hsuan, et al.
Publicado: (2016)

Regulation of Jun and Fos AP-1 transcription factors by JNK MAPKs signaling cascade in areca nut extract treated KB cells
por: Nagesh, Rashmi, et al.
Publicado: (2021)

Multifaceted Mechanisms of Areca Nuts in Oral Carcinogenesis: the Molecular Pathology from Precancerous Condition to Malignant Transformation
por: Li, Yi-Chen, et al.
Publicado: (2019)

Assessment of Salivary Flow Rate and pH Among Areca Nut Chewers and Oral Submucous Fibrosis Subjects: A Comparative Study
por: Abdul Khader, Nishat Fatima, et al.
Publicado: (2015)

Inhibition of Tanshinone IIA, Salvianolic Acid A and Salvianolic Acid B on Areca Nut Extract-Induced Oral Submucous Fibrosis in Vitro
por: Dai, Jian-Ping, et al.
Publicado: (2015)

Effect of copper-based fungicide (bordeaux mixture) spray on the total copper content of areca nut: Implications in increasing prevalence of oral submucous fibrosis
por: Mathew, Philips, et al.
Publicado: (2015)

A review of the systemic adverse effects of areca nut or betel nut
por: Garg, Apurva, et al.
Publicado: (2014)

Study of salivary arecoline in areca nut chewers
por: Venkatesh, Deepak, et al.
Publicado: (2018)

The Controversial Roles of Areca Nut: Medicine or Toxin?
por: Liu, Pei-Feng, et al.
Publicado: (2023)

Simvastatin Attenuates Areca Nut Extract-Induced Subdermal Fibrosis in Mice by Targeting TGF-β Signaling Pathways
por: Chang, Chi-Hua, et al.
Publicado: (2023)

Two New Flavonoids from the Nuts of Areca catechu
por: Yuan, Mengfei, et al.
Publicado: (2019)

Association of Areca Nut Chewing With Risk of Erectile Dysfunction
por: Huang, Yung-Jui, et al.
Publicado: (2017)

ANKRD49 promotes the metastasis of NSCLC via activating JNK-ATF2/c-Jun-MMP-2/9 axis
por: Sun, Jia, et al.
Publicado: (2023)

Impacts of Autophagy-Inducing Ingredient of Areca Nut on Tumor Cells
por: Yen, Ching-Yu, et al.
Publicado: (2015)

Mechanistic and compositional studies of the autophagy-inducing areca nut ingredient
por: Chiu, Chang-Ta, et al.
Publicado: (2020)

Study on Dissociation and Chemical Structural Characteristics of Areca Nut Husk
por: Yuan, Jianbo, et al.
Publicado: (2023)

A Review of Intervention Strategies for Areca Nut Use Cessation
por: Dhingra, Kriti, et al.
Publicado: (2023)

Is areca innocent? The effect of areca (betel) nut chewing in a population of pregnant women on the Thai–Myanmar border
por: Chue, Amy L., et al.
Publicado: (2012)

Antiovulatory and abortifacient effects of Areca catechu (betel nut) in female rats
por: Shrestha, Jyoti, et al.
Publicado: (2010)

Areca nut chewing and metabolic syndrome: evidence of a harmful relationship
por: Shafique, Kashif, et al.
Publicado: (2013)

Various terminologies associated with areca nut and tobacco chewing: A review
por: Patidar, Kalpana A, et al.
Publicado: (2015)

Areca nut extract protects against ovariectomy-induced osteoporosis in mice
por: Li, Shuyu, et al.
Publicado: (2017)

The Protective Effect of Antioxidants in Areca Nut Extract-Induced Oral Carcinogenesis
por: Kim, Dokyeong, et al.
Publicado: (2020)

Risk of liver disease in areca nut habitual: A systematic review
por: Khasbage, Suwarna B Dangore, et al.
Publicado: (2022)

Areca Nut and Oral Cancer: Evidence from Studies Conducted in Humans
por: Warnakulasuriya, S., et al.
Publicado: (2022)

Self-Confidence, Not Self-Awareness, Is Negatively Associated With Areca Nut Dependence
por: Hsu, Chen-Yuan, et al.
Publicado: (2022)

Potential Role of Host Microbiome in Areca Nut-Associated Carcinogenesis and Addiction
por: Chen, Lihui, et al.
Publicado: (2022)

Chemical Composition of Areca Nut and Its Adverse Effects on Human Health
por: Dangore-Khasbage, Suwarna, et al.
Publicado: (2023)

Exploring Possible Diagnostic Precancerous Biomarkers for Oral Submucous Fibrosis: A Narrative Review
por: You, Jie-Ru, et al.
Publicado: (2023)

Substrate Stiffness Modulates TGF-β Activation and ECM-Associated Gene Expression in Fibroblasts
por: Verma, Brijesh Kumar, et al.
Publicado: (2023)

Association Between Grading of Oral Submucous Fibrosis With Frequency and Consumption of Areca Nut and Its Derivatives in a Wide Age Group: A Multi-centric Cross Sectional Study From Karachi, Pakistan
por: Hosein, Mervyn, et al.
Publicado: (2015)

Prevalence of areca nut chewing in the middle school-going children of Indore, India
por: Khandelwal, Ashok, et al.
Publicado: (2012)

Peroxidase as the Major Protein Constituent in Areca Nut and Identification of Its Natural Substrates
por: Liu, Yu-Ching, et al.
Publicado: (2013)

Effect of areca nut chewing and maximal mouth opening in schoolgoing children in Ahmedabad
por: Khan, Azizfatema Munawer, et al.
Publicado: (2016)

Evaluation of Successfulness of Capacity Building Programmes on Smokeless Tobacco and Areca Nut Cessation
por: Jayasinghe, Ruwan Duminda, et al.
Publicado: (2021)

Carcinogenic Effects of Areca Nut and Its Metabolites: A Review of the Experimental Evidence
por: Senevirathna, Kalpani, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_n4q97iqnhqhqj8d7oi3871qdgf