14-3-3ζ regulates the mitochondrial respiratory reserve linked to platelet phosphatidylserine exposure and procoagulant function

The 14-3-3 family of adaptor proteins regulate diverse cellular functions including cell proliferation, metabolism, adhesion and apoptosis. Platelets express numerous 14-3-3 isoforms, including 14-3-3ζ, which has previously been implicated in regulating GPIbα function. Here we show an important role...

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Detalles Bibliográficos
Autores principales: Schoenwaelder, Simone M., Darbousset, Roxane, Cranmer, Susan L., Ramshaw, Hayley S., Orive, Stephanie L., Sturgeon, Sharelle, Yuan, Yuping, Yao, Yu, Krycer, James R., Woodcock, Joanna, Maclean, Jessica, Pitson, Stuart, Zheng, Zhaohua, Henstridge, Darren C., van der Wal, Dianne, Gardiner, Elizabeth E., Berndt, Michael C., Andrews, Robert K., James, David E., Lopez, Angel F., Jackson, Shaun P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052641/
https://www.ncbi.nlm.nih.gov/pubmed/27670677
http://dx.doi.org/10.1038/ncomms12862

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