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CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages

Interleukin-1β (IL-1β) is a proinflammatory cytokine required for host control of bacterial infections, and its production must be tightly regulated to prevent excessive inflammation. Here we show that caspase recruitment domain-containing protein 9 (CARD9), a protein associated with induction of pr...

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Detalles Bibliográficos
Autores principales: Pereira, Milton, Tourlomousis, Panagiotis, Wright, John, P. Monie, Tom, Bryant, Clare E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052644/
https://www.ncbi.nlm.nih.gov/pubmed/27670879
http://dx.doi.org/10.1038/ncomms12874