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CARD9 negatively regulates NLRP3-induced IL-1β production on Salmonella infection of macrophages
Interleukin-1β (IL-1β) is a proinflammatory cytokine required for host control of bacterial infections, and its production must be tightly regulated to prevent excessive inflammation. Here we show that caspase recruitment domain-containing protein 9 (CARD9), a protein associated with induction of pr...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Nature Publishing Group
2016
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052644/ https://www.ncbi.nlm.nih.gov/pubmed/27670879 http://dx.doi.org/10.1038/ncomms12874 |