DNA annealing by Redβ is insufficient for homologous recombination and the additional requirements involve intra- and inter-molecular interactions

Single strand annealing proteins (SSAPs) like Redβ initiate homologous recombination by annealing complementary DNA strands. We show that C-terminally truncated Redβ, whilst still able to promote annealing and nucleoprotein filament formation, is unable to mediate homologous recombination. Mutations...

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Detalles Bibliográficos
Autores principales: Subramaniam, Sivaraman, Erler, Axel, Fu, Jun, Kranz, Andrea, Tang, Jing, Gopalswamy, Mohanraj, Ramakrishnan, Saminathan, Keller, Adrian, Grundmeier, Guido, Müller, Daniel, Sattler, Michael, Stewart, A. Francis
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052646/
https://www.ncbi.nlm.nih.gov/pubmed/27708411
http://dx.doi.org/10.1038/srep34525

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