Structure–function insights reveal the human ribosome as a cancer target for antibiotics

Many antibiotics in clinical use target the bacterial ribosome by interfering with the protein synthesis machinery. However, targeting the human ribosome in the case of protein synthesis deregulations such as in highly proliferating cancer cells has not been investigated at the molecular level up to...

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Detalles Bibliográficos
Autores principales: Myasnikov, Alexander G., Kundhavai Natchiar, S., Nebout, Marielle, Hazemann, Isabelle, Imbert, Véronique, Khatter, Heena, Peyron, Jean-François, Klaholz, Bruno P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052680/
https://www.ncbi.nlm.nih.gov/pubmed/27665925
http://dx.doi.org/10.1038/ncomms12856

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052680/
https://www.ncbi.nlm.nih.gov/pubmed/27665925
http://dx.doi.org/10.1038/ncomms12856

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