Cargando…

The structural basis for CD36 binding by the malaria parasite

CD36 is a scavenger receptor involved in fatty acid metabolism, innate immunity and angiogenesis. It interacts with lipoprotein particles and facilitates uptake of long chain fatty acids. It is also the most common target of the PfEMP1 proteins of the malaria parasite, Plasmodium falciparum, tetheri...

Descripción completa

Detalles Bibliográficos
Autores principales:	Hsieh, Fu-Lien, Turner, Louise, Bolla, Jani Reddy, Robinson, Carol V., Lavstsen, Thomas, Higgins, Matthew K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2016
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052687/ https://www.ncbi.nlm.nih.gov/pubmed/27667267 http://dx.doi.org/10.1038/ncomms12837

Ejemplares similares

Severe malaria is associated with parasite binding to endothelial protein C receptor
por: Turner, Louise, et al.
Publicado: (2013)

91074 Identification of monoclonal antibodies with broad reactivity against the malaria parasite variant surface antigen responsible for severe malaria
por: Reyes, Raphael, et al.
Publicado: (2021)

Towards an anti-disease malaria vaccine
por: Lennartz, Frank, et al.
Publicado: (2017)

CD36—A Host Receptor Necessary for Malaria Parasites to Establish and Maintain Infection
por: Bachmann, Anna, et al.
Publicado: (2022)

Sickle-trait hemoglobin reduces adhesion to both CD36 and EPCR by Plasmodium falciparum-infected erythrocytes
por: Petersen, Jens E. V., et al.
Publicado: (2021)

Parasite Burden and CD36-Mediated Sequestration Are Determinants of Acute Lung Injury in an Experimental Malaria Model
por: Lovegrove, Fiona E., et al.
Publicado: (2008)

Structural Conservation Despite Huge Sequence Diversity Allows EPCR Binding by the PfEMP1 Family Implicated in Severe Childhood Malaria
por: Lau, Clinton K.Y., et al.
Publicado: (2015)

Reduced CD36-dependent tissue sequestration of Plasmodium-infected erythrocytes is detrimental to malaria parasite growth in vivo
por: Fonager, Jannik, et al.
Publicado: (2012)

CD36 Contributes to Malaria Parasite-Induced Pro-Inflammatory Cytokine Production and NK and T Cell Activation by Dendritic Cells
por: Gowda, Nagaraj M., et al.
Publicado: (2013)

Why it might be bad for brain cells to eat malaria parasites
por: Higgins, Matthew K.
Publicado: (2021)

Structure-Guided Design of a Synthetic Mimic of an Endothelial Protein C Receptor-Binding PfEMP1 Protein
por: Barber, Natalie M., et al.
Publicado: (2021)

Molecular basis of fosmidomycin's action on the human malaria parasite Plasmodium falciparum
por: Umeda, Tomonobu, et al.
Publicado: (2011)

The Different Effects of Substrates and Nucleotides on the Complex Formation of ABC Transporters
por: Fiorentino, Francesco, et al.
Publicado: (2019)

Molecular Architecture of a Complex between an Adhesion Protein from the Malaria Parasite and Intracellular Adhesion Molecule 1
por: Brown, Alan, et al.
Publicado: (2013)

Structure of the Plasmodium-interspersed repeat proteins of the malaria parasite
por: Harrison, Thomas E., et al.
Publicado: (2020)

Plasmodium falciparum EPCR-binding PfEMP1 expression increases with malaria disease severity and is elevated in retinopathy negative cerebral malaria
por: Shabani, Estela, et al.
Publicado: (2017)

The molecular basis of regulation of bacterial capsule assembly by Wzc
por: Yang, Yun, et al.
Publicado: (2021)

Assembly and regulation of the chlorhexidine-specific efflux pump AceI
por: Bolla, Jani Reddy, et al.
Publicado: (2020)

The cellular and molecular basis for malaria parasite invasion of the human red blood cell
por: Cowman, Alan F., et al.
Publicado: (2012)

Lipoprotein binding preference of CD36 is altered by filipin treatment
por: Zhang, Jianshe, et al.
Publicado: (2008)

Insight into the mechanism of lipids binding and uptake by CD36 receptor
por: Tarhda, Zineb, et al.
Publicado: (2015)

Binding of Plasmodium falciparum to CD36 can be shielded by the glycocalyx
por: Hempel, Casper, et al.
Publicado: (2017)

Low-Bone-Mass Phenotype of Deficient Mice for the Cluster of Differentiation 36 (CD36)
por: Kevorkova, Olha, et al.
Publicado: (2013)

Structural basis of malaria parasite phenylalanine tRNA-synthetase inhibition by bicyclic azetidines
por: Sharma, Manmohan, et al.
Publicado: (2021)

Structure-Guided Identification of a Family of Dual Receptor-Binding PfEMP1 that Is Associated with Cerebral Malaria
por: Lennartz, Frank, et al.
Publicado: (2017)

Malaria and Malaria Parasites
Publicado: (1901)

The neurorepellent, Slit2, prevents macrophage lipid loading by inhibiting CD36-dependent binding and internalization of oxidized low-density lipoprotein
por: Yusuf, Bushra, et al.
Publicado: (2021)

The Structure of a Chondroitin Sulfate-binding Domain Important in Placental Malaria
por: Higgins, Matthew K.
Publicado: (2008)

Structural basis for RIFIN-mediated activation of LILRB1 in malaria
por: Harrison, Thomas E., et al.
Publicado: (2020)

The structure of nontypeable Haemophilus influenzae SapA in a closed conformation reveals a constricted ligand-binding cavity and a novel RNA binding motif
por: Lukacik, Petra, et al.
Publicado: (2021)

Humanized CD36 (hCD36) mouse model supports the preclinical evaluation of therapeutic candidates targeting CD36
por: Xie, Xiulong, et al.
Publicado: (2023)

The structure of a LAIR1-containing human antibody reveals a novel mechanism of antigen recognition
por: Hsieh, Fu-Lien, et al.
Publicado: (2017)

Structural Basis for Disparate Sugar-Binding Specificities in the Homologous Cargo Receptors ERGIC-53 and VIP36
por: Satoh, Tadashi, et al.
Publicado: (2014)

Genome sequence of Anopheles sinensis provides insight into genetics basis of mosquito competence for malaria parasites
por: Zhou, Dan, et al.
Publicado: (2014)

A Basis for Rapid Clearance of Circulating Ring-Stage Malaria Parasites by the Spiroindolone KAE609
por: Zhang, Rou, et al.
Publicado: (2016)

Cellulose filtration of blood from malaria patients for improving ex vivo growth of Plasmodium falciparum parasites
por: Mkumbaye, Sixbert I., et al.
Publicado: (2017)

Structural basis of malaria RIFIN binding by LILRB1-containing antibodies
por: Chen, Yiwei, et al.
Publicado: (2021)

The Malaria Parasite
Publicado: (1900)

CD8(+) T cell activation by murine erythroblasts infected with malaria parasites
por: Imai, Takashi, et al.
Publicado: (2013)

HDP—A Novel Heme Detoxification Protein from the Malaria Parasite
por: Jani, Dewal, et al.
Publicado: (2008)

Cannot write session to /tmp/vufind_sessions/sess_bs66l38i27388grijqd5teuns6