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Probing the mechanisms for the selectivity and promiscuity of methyl parathion hydrolase

Diverse organophosphate hydrolases have convergently evolved the ability to hydrolyse man-made organophosphates. Thus, these enzymes are attractive model systems for studying the factors shaping enzyme functional evolution. Methyl parathion hydrolase (MPH) is an enzyme from the metallo-β-lactamase s...

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Detalles Bibliográficos
Autores principales:	Purg, Miha, Pabis, Anna, Baier, Florian, Tokuriki, Nobuhiko, Jackson, Colin, Kamerlin, Shina Caroline Lynn
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Royal Society 2016
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052733/ https://www.ncbi.nlm.nih.gov/pubmed/27698033 http://dx.doi.org/10.1098/rsta.2016.0150

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