ANGPTL2 activity in cardiac pathologies accelerates heart failure by perturbing cardiac function and energy metabolism

A cardioprotective response that alters ventricular contractility or promotes cardiomyocyte enlargement occurs with increased workload in conditions such as hypertension. When that response is excessive, pathological cardiac remodelling occurs, which can progress to heart failure, a leading cause of...

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Detalles Bibliográficos
Autores principales: Tian, Zhe, Miyata, Keishi, Kadomatsu, Tsuyoshi, Horiguchi, Haruki, Fukushima, Hiroyuki, Tohyama, Shugo, Ujihara, Yoshihiro, Okumura, Takahiro, Yamaguchi, Satoshi, Zhao, Jiabin, Endo, Motoyoshi, Morinaga, Jun, Sato, Michio, Sugizaki, Taichi, Zhu, Shunshun, Terada, Kazutoyo, Sakaguchi, Hisashi, Komohara, Yoshihiro, Takeya, Motohiro, Takeda, Naoki, Araki, Kimi, Manabe, Ichiro, Fukuda, Keiichi, Otsu, Kinya, Wada, Jun, Murohara, Toyoaki, Mohri, Satoshi, Yamashita, Jun K., Sano, Motoaki, Oike, Yuichi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5052800/
https://www.ncbi.nlm.nih.gov/pubmed/27677409
http://dx.doi.org/10.1038/ncomms13016

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