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Intranasal immunization with recombinant Toxoplasma gondii actin depolymerizing factor confers protective efficacy against toxoplasmosis in mice

BACKGROUND: Toxoplasma gondii is an opportunistic protozoan closely associated with AIDS and vertical transmission. T. gondii actin depolymerizing factor (TgADF) plays an important role in actin cytoskeleton remodeling, and it is required to invade host cells. TgADF was a promising vaccine candidate...

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Detalles Bibliográficos
Autores principales: Liu, Zhuanzhuan, Yin, Litian, Li, Yaqing, Yuan, Fei, Zhang, Xiaofan, Ma, Jiazhi, Liu, Hongmei, Wang, Yanjuan, Zheng, Kuiyang, Cao, Jianping
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053087/
https://www.ncbi.nlm.nih.gov/pubmed/27716047
http://dx.doi.org/10.1186/s12865-016-0173-9

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