Prevalence and Phenotypic Expression of Mutations in the MYH7, MYBPC3 and TNNT2 Genes in Families with Hypertrophic Cardiomyopathy in the South of Brazil: A Cross-Sectional Study

BACKGROUND: Mutations in sarcomeric genes are found in 60-70% of individuals with familial forms of hypertrophic cardiomyopathy (HCM). However, this estimate refers to northern hemisphere populations. The molecular-genetic profile of HCM has been subject of few investigations in Brazil, particularly...

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Detalles Bibliográficos
Autores principales: Mattos, Beatriz Piva e, Scolari, Fernando Luís, Torres, Marco Antonio Rodrigues, Simon, Laura, de Freitas, Valéria Centeno, Giugliani, Roberto, Matte, Úrsula
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Sociedade Brasileira de Cardiologia - SBC 2016
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053194/
https://www.ncbi.nlm.nih.gov/pubmed/27737317
http://dx.doi.org/10.5935/abc.20160133

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