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Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T

MRI is finding increased clinical use in neonatal populations; the extent to which electromagnetic models used for quantification of specific absorption rate (SAR) by commercial MRI scanners accurately reflect this alternative scenario is unclear. This study investigates how SAR predictions relating...

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Autores principales: Malik, Shaihan J., Beqiri, Arian, Price, Anthony N., Teixeira, Jose Nuno, Hand, Jeffrey W., Hajnal, Joseph V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2015
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053241/
https://www.ncbi.nlm.nih.gov/pubmed/25594939
http://dx.doi.org/10.1002/nbm.3256
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author Malik, Shaihan J.
Beqiri, Arian
Price, Anthony N.
Teixeira, Jose Nuno
Hand, Jeffrey W.
Hajnal, Joseph V.
author_facet Malik, Shaihan J.
Beqiri, Arian
Price, Anthony N.
Teixeira, Jose Nuno
Hand, Jeffrey W.
Hajnal, Joseph V.
author_sort Malik, Shaihan J.
collection PubMed
description MRI is finding increased clinical use in neonatal populations; the extent to which electromagnetic models used for quantification of specific absorption rate (SAR) by commercial MRI scanners accurately reflect this alternative scenario is unclear. This study investigates how SAR predictions relating to adults can be related to neonates under differing conditions when imaged using 1.5 T and 3 T MRI scanners. Electromagnetic simulations were produced in neonatal subjects of different sizes and positions within a generic MRI body transmit device operating at both 64 MHz and 128 MHz, corresponding to 1.5 T and 3 T MRI scanners, respectively. An adult model was also simulated, as was a spherical salt‐water phantom, which was also used in a calorimetry experiment. The SAR in neonatal subjects was found to be less than that experienced in an adult in all scenarios; however, the overestimation factor was variable. For example a 3 T body scan resulting in local 10 g SAR of 10.1 W kg(−1) in an adult would deposit 2.6 W kg(−1) in a neonate: an approximately fourfold difference. The SAR experienced by neonatal subjects undergoing MRI is lower than that in adults in equivalent situations. If the safety of such procedures is assessed using adult‐appropriate models then the result is a conservative estimate. © 2015 The Authors. NMR in Biomedicine published by John Wiley & Sons, Ltd.
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spelling pubmed-50532412016-10-19 Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T Malik, Shaihan J. Beqiri, Arian Price, Anthony N. Teixeira, Jose Nuno Hand, Jeffrey W. Hajnal, Joseph V. NMR Biomed Research Articles MRI is finding increased clinical use in neonatal populations; the extent to which electromagnetic models used for quantification of specific absorption rate (SAR) by commercial MRI scanners accurately reflect this alternative scenario is unclear. This study investigates how SAR predictions relating to adults can be related to neonates under differing conditions when imaged using 1.5 T and 3 T MRI scanners. Electromagnetic simulations were produced in neonatal subjects of different sizes and positions within a generic MRI body transmit device operating at both 64 MHz and 128 MHz, corresponding to 1.5 T and 3 T MRI scanners, respectively. An adult model was also simulated, as was a spherical salt‐water phantom, which was also used in a calorimetry experiment. The SAR in neonatal subjects was found to be less than that experienced in an adult in all scenarios; however, the overestimation factor was variable. For example a 3 T body scan resulting in local 10 g SAR of 10.1 W kg(−1) in an adult would deposit 2.6 W kg(−1) in a neonate: an approximately fourfold difference. The SAR experienced by neonatal subjects undergoing MRI is lower than that in adults in equivalent situations. If the safety of such procedures is assessed using adult‐appropriate models then the result is a conservative estimate. © 2015 The Authors. NMR in Biomedicine published by John Wiley & Sons, Ltd. John Wiley and Sons Inc. 2015-03 2015-01-16 /pmc/articles/PMC5053241/ /pubmed/25594939 http://dx.doi.org/10.1002/nbm.3256 Text en © 2015 The Authors. NMR in Biomedicine published by John Wiley & Sons, Ltd. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Articles
Malik, Shaihan J.
Beqiri, Arian
Price, Anthony N.
Teixeira, Jose Nuno
Hand, Jeffrey W.
Hajnal, Joseph V.
Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T
title Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T
title_full Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T
title_fullStr Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T
title_full_unstemmed Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T
title_short Specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 T and 3 T
title_sort specific absorption rate in neonates undergoing magnetic resonance procedures at 1.5 t and 3 t
topic Research Articles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053241/
https://www.ncbi.nlm.nih.gov/pubmed/25594939
http://dx.doi.org/10.1002/nbm.3256
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