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Filaggrin failure – from ichthyosis vulgaris to atopic eczema and beyond
The main proteinaceous component of the keratohyalin granules within the granular layer keratinocytes of the epidermis is the giant, repetitive polyprotein profilaggrin. When granular layer cells commit to terminal differentiation to form the flattened squames of the stratum corneum, profilaggrin is...
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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John Wiley and Sons Inc.
2016
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053269/ https://www.ncbi.nlm.nih.gov/pubmed/27667308 http://dx.doi.org/10.1111/bjd.14997 |