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Retroviral integration: Site matters: Mechanisms and consequences of retroviral integration site selection

Here, we review genomic target site selection during retroviral integration as a multistep process in which specific biases are introduced at each level. The first asymmetries are introduced when the virus takes a specific route into the nucleus. Next, by co‐opting distinct host cofactors, the integ...

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Detalles Bibliográficos
Autores principales:	Demeulemeester, Jonas, De Rijck, Jan, Gijsbers, Rik, Debyser, Zeger
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	John Wiley and Sons Inc. 2015
Materias:	Prospects & Overviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053271/ https://www.ncbi.nlm.nih.gov/pubmed/26293289 http://dx.doi.org/10.1002/bies.201500051

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