Transcribing RNA polymerase III observed by electron cryomicroscopy

Electron cryomicroscopy reconstructions of elongating RNA polymerase (Pol) III at 3.9 Å resolution and of unbound Pol III (apo Pol III) in two distinct conformations at 4.6 Å and 4.7 Å resolution allow the construction of complete atomic models of Pol III and provide new functional insights into the...

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Autores principales: Hoffmann, Niklas A., Jakobi, Arjen J., Vorländer, Matthias K., Sachse, Carsten, Müller, Christoph W.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Structural Snapshot
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053293/
https://www.ncbi.nlm.nih.gov/pubmed/27059519
http://dx.doi.org/10.1111/febs.13732
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author Hoffmann, Niklas A.
Jakobi, Arjen J.
Vorländer, Matthias K.
Sachse, Carsten
Müller, Christoph W.
author_facet Hoffmann, Niklas A.
Jakobi, Arjen J.
Vorländer, Matthias K.
Sachse, Carsten
Müller, Christoph W.
author_sort Hoffmann, Niklas A.
collection PubMed
description Electron cryomicroscopy reconstructions of elongating RNA polymerase (Pol) III at 3.9 Å resolution and of unbound Pol III (apo Pol III) in two distinct conformations at 4.6 Å and 4.7 Å resolution allow the construction of complete atomic models of Pol III and provide new functional insights into the adaption of Pol III to fulfill its specific transcription tasks.
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spelling pubmed-50532932016-10-19 Transcribing RNA polymerase III observed by electron cryomicroscopy Hoffmann, Niklas A. Jakobi, Arjen J. Vorländer, Matthias K. Sachse, Carsten Müller, Christoph W. FEBS J Structural Snapshot Electron cryomicroscopy reconstructions of elongating RNA polymerase (Pol) III at 3.9 Å resolution and of unbound Pol III (apo Pol III) in two distinct conformations at 4.6 Å and 4.7 Å resolution allow the construction of complete atomic models of Pol III and provide new functional insights into the adaption of Pol III to fulfill its specific transcription tasks. John Wiley and Sons Inc. 2016-04-28 2016-08 /pmc/articles/PMC5053293/ /pubmed/27059519 http://dx.doi.org/10.1111/febs.13732 Text en © 2016 The Authors. The FEBS Journal published by John Wiley & Sons Ltd on behalf of Federation of European Biochemical Societies. This is an open access article under the terms of the Creative Commons Attribution (http://creativecommons.org/licenses/by/4.0/) License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.
spellingShingle Structural Snapshot
Hoffmann, Niklas A.
Jakobi, Arjen J.
Vorländer, Matthias K.
Sachse, Carsten
Müller, Christoph W.
Transcribing RNA polymerase III observed by electron cryomicroscopy
title Transcribing RNA polymerase III observed by electron cryomicroscopy
title_full Transcribing RNA polymerase III observed by electron cryomicroscopy
title_fullStr Transcribing RNA polymerase III observed by electron cryomicroscopy
title_full_unstemmed Transcribing RNA polymerase III observed by electron cryomicroscopy
title_short Transcribing RNA polymerase III observed by electron cryomicroscopy
title_sort transcribing rna polymerase iii observed by electron cryomicroscopy
topic Structural Snapshot
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053293/
https://www.ncbi.nlm.nih.gov/pubmed/27059519
http://dx.doi.org/10.1111/febs.13732
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