Gut microbiome analysis in neuromyelitis optica reveals overabundance of Clostridium perfringens

T cells from neuromyelitis optica (NMO) patients, which recognize the immunodominant epitope of aquaporin‐4, exhibit Th17 polarization and cross‐react with a homologous sequence of a Clostridium perfringens adenosine triphosphate‐binding cassette transporter. Therefore, this commensal microbe might...

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Detalles Bibliográficos
Autores principales: Cree, Bruce A. C., Spencer, Collin M., Varrin‐Doyer, Michel, Baranzini, Sergio E., Zamvil, Scott S.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Brief Communications
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053302/
https://www.ncbi.nlm.nih.gov/pubmed/27398819
http://dx.doi.org/10.1002/ana.24718

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