Enlargement of the Axial Length and Altered Ultrastructural Features of the Sclera in a Mutant Lumican Transgenic Mouse Model

Lumican (LUM) is a candidate gene for myopia in the MYP3 locus. In this study, a mutant lumican (L199P) transgenic mouse model was established to investigate the axial length changes and ultrastructural features of the sclera. The mouse model was established by pronuclear microinjection. Transgenic...

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Detalles Bibliográficos
Autores principales: Song, Yanzheng, Zhang, Fengju, Zhao, Yanyan, Sun, Mingshen, Tao, Jun, Liang, Yanchuang, Ma, Ling, Yu, Yanqiu, Wang, Jianhua, Hao, Junfeng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053428/
https://www.ncbi.nlm.nih.gov/pubmed/27711221
http://dx.doi.org/10.1371/journal.pone.0163165

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