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Fumarate Production by Torulopsis glabrata: Engineering Heterologous Fumarase Expression and Improving Acid Tolerance

Fumarate is a well-known biomass building block compound. However, the poor catalytic efficiency of fumarase is one of the major factors preventing its widespread production. To address this issue, we selected residues (159)HPND(162) of fumarase from Rhizopus oryzae as targets for site-directed muta...

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Detalles Bibliográficos
Autores principales: Chen, Xiulai, Song, Wei, Gao, Cong, Qin, Wen, Luo, Qiuling, Liu, Jia, Liu, Liming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053504/
https://www.ncbi.nlm.nih.gov/pubmed/27711153
http://dx.doi.org/10.1371/journal.pone.0164141