Cargando…

Integrated Left Ventricular Global Transcriptome and Proteome Profiling in Human End-Stage Dilated Cardiomyopathy

AIMS: The disease pathways leading to idiopathic dilated cardiomyopathy (DCM) are still elusive. The present study investigated integrated global transcriptional and translational changes in human DCM for disease biomarker discovery. METHODS: We used identical myocardial tissues from five DCM hearts...

Descripción completa

Detalles Bibliográficos
Autores principales:	Colak, Dilek, Alaiya, Ayodele A., Kaya, Namik, Muiya, Nzioka P., AlHarazi, Olfat, Shinwari, Zakia, Andres, Editha, Dzimiri, Nduna
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2016
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053516/ https://www.ncbi.nlm.nih.gov/pubmed/27711126 http://dx.doi.org/10.1371/journal.pone.0162669

Ejemplares similares

The 3′-UTR of the adiponectin Q gene harbours susceptibility loci for atherosclerosis and its metabolic risk traits
por: Muiya, Nzioka, et al.
Publicado: (2013)

The Affymetrix DMET Plus Platform Reveals Unique Distribution of ADME-Related Variants in Ethnic Arabs
por: Wakil, Salma M., et al.
Publicado: (2015)

New susceptibility locus for obesity and dyslipidaemia on chromosome 3q22.3
por: Alshahid, Maie, et al.
Publicado: (2013)

A study of the role of GATA4 polymorphism in cardiovascular metabolic disorders
por: Muiya, Nzioka P, et al.
Publicado: (2013)

Data on common variants associated with coronary artery disease/myocardial infarction in ethnic Arabs
por: Wakil, Salma M., et al.
Publicado: (2016)

Proteomic Profiling of the First Human Dental Pulp Mesenchymal Stem/Stromal Cells from Carbonic Anhydrase II Deficiency Osteopetrosis Patients
por: Alkhayal, Zikra, et al.
Publicado: (2020)

A New Susceptibility Locus for Myocardial Infarction, Hypertension, Type 2 Diabetes Mellitus, and Dyslipidemia on Chromosome 12q24
por: Wakil, Salma M., et al.
Publicado: (2014)

Transcriptomic data analysis coupled with copy number aberrations reveals a blood-based 17-gene signature for diagnosis and prognosis of patients with colorectal cancer
por: Kaya, Ibrahim H., et al.
Publicado: (2023)

PD‐L1 promotes OCT4 and Nanog expression in breast cancer stem cells by sustaining PI3K/AKT pathway activation
por: Almozyan, Sheema, et al.
Publicado: (2017)

Integrated Analysis of Transcriptomic and Genomic Data Reveals Blood Biomarkers With Diagnostic and Prognostic Potential in Non-small Cell Lung Cancer
por: Kaya, Ibrahim H., et al.
Publicado: (2022)

Carbonic Anhydrase II Activators in Osteopetrosis Treatment: A Review
por: Alkhayal, Zikra, et al.
Publicado: (2023)

Fluconazole-Induced Protein Changes in Osteogenic and Immune Metabolic Pathways of Dental Pulp Mesenchymal Stem Cells of Osteopetrosis Patients
por: Alkhayal, Zikra, et al.
Publicado: (2023)

Mutation in FBXO32 causes dilated cardiomyopathy through up-regulation of ER-stress mediated apoptosis
por: Al-Yacoub, Nadya, et al.
Publicado: (2021)

A substitution mutation in cardiac ubiquitin ligase, FBXO32, is associated with an autosomal recessive form of dilated cardiomyopathy
por: Al-Hassnan, Zuhair N., et al.
Publicado: (2016)

Association of the angiotensinogen gene polymorphism with atherosclerosis and its risk traits in the Saudi population
por: Al-Najai, Mohammed, et al.
Publicado: (2013)

A Network-Based Methodology to Identify Subnetwork Markers for Diagnosis and Prognosis of Colorectal Cancer
por: Al-Harazi, Olfat, et al.
Publicado: (2021)

Identification of Gene Signature as Diagnostic and Prognostic Blood Biomarker for Early Hepatocellular Carcinoma Using Integrated Cross-Species Transcriptomic and Network Analyses
por: Al-Harazi, Olfat, et al.
Publicado: (2021)

LC-MS/MS proteomic analysis revealed novel associations of 37 proteins with T2DM and notable upregulation of immunoglobulins
por: Abdulwahab, Rabab Asghar, et al.
Publicado: (2019)

The selective cytotoxic anti-cancer properties and proteomic analysis of Trigonella Foenum-Graecum
por: Alsemari, Abdulaziz, et al.
Publicado: (2014)

Anti-Inflammatory Effect of Specialized Proresolving Lipid Mediators on Mesenchymal Stem Cells: An In Vitro Study
por: AlZahrani, Shahd, et al.
Publicado: (2022)

Sex-Biased Expression of Genes Allocated in the Autosomal Chromosomes: Blood LC-MS/MS Protein Profiling in Healthy Subjects
por: Giha, Hayder A., et al.
Publicado: (2023)

FBXO32, encoding a member of the SCF complex, is mutated in dilated cardiomyopathy
por: Al-Yacoub, Nadya, et al.
Publicado: (2016)

In-depth proteomic profiling of left ventricular tissues in human end-stage dilated cardiomyopathy
por: Liu, Shanshan, et al.
Publicado: (2017)

Proteomic Analysis of Morphologically Changed Tissues after Prolonged Dexamethasone Treatment
por: Malkawi, Abeer K., et al.
Publicado: (2019)

Inhibition of signaling downstream of beta‐2 adrenoceptor by propranolol in prostate cancer cells
por: Alaskar, Aljoharah, et al.
Publicado: (2022)

Electrical Ventricular Remodeling in Dilated Cardiomyopathy
por: Mages, Christine, et al.
Publicado: (2021)

Comparison of two dependent within subject coefficients of variation to evaluate the reproducibility of measurement devices
por: Shoukri, Mohamed M, et al.
Publicado: (2008)

Bidirectional crosstalk between PD-L1 expression and epithelial to mesenchymal transition: Significance in claudin-low breast cancer cells
por: Alsuliman, Abdullah, et al.
Publicado: (2015)

RNA-Seq transcriptome profiling in three liver regeneration models in rats: comparative analysis of partial hepatectomy, ALLPS, and PVL
por: Colak, Dilek, et al.
Publicado: (2020)

Publisher Correction: RNA-Seq transcriptome profiling in three liver regeneration models in rats: comparative analysis of partial hepatectomy, ALLPS, and PVL
por: Colak, Dilek, et al.
Publicado: (2020)

A novel mutation and first report of dilated cardiomyopathy in ALG6-CDG (CDG-Ic): a case report
por: Al-Owain, Mohammed, et al.
Publicado: (2010)

Arrhythmogenic Right Ventricular Cardiomyopathy: Characterization of Left Ventricular Phenotype and Differential Diagnosis With Dilated Cardiomyopathy
por: Cipriani, Alberto, et al.
Publicado: (2020)

Isolated Right Ventricular Dilated Cardiomyopathy: An Early Diagnosis
por: Briongos Figuero, Sem, et al.
Publicado: (2015)

Evaluation of left ventricular strain in patients with dilated cardiomyopathy
por: Yu, Yaohan, et al.
Publicado: (2017)

Expression profiling of WD40 family genes including DDB1- and CUL4- associated factor (DCAF) genes in mice and human suggests important regulatory roles in testicular development and spermatogenesis
por: Mistry, Bhavesh V., et al.
Publicado: (2020)

Left ventricular strain echocardiography in advanced uremic cardiomyopathy compared to dilated cardiomyopathy
por: Mohammadi, Rizan, et al.
Publicado: (2023)

Alterations in the Plasma Proteome Induced by SARS-CoV-2 and MERS-CoV Reveal Biomarkers for Disease Outcomes for COVID-19 Patients
por: Alaiya, Ayodele, et al.
Publicado: (2021)

Transcriptomic Signatures of End-Stage Human Dilated Cardiomyopathy Hearts with and without Left Ventricular Assist Device Support
por: Parikh, Mihir, et al.
Publicado: (2022)

Decreased Left Ventricular Torsion and Untwisting in Children with Dilated Cardiomyopathy
por: Jin, Seon Mi, et al.
Publicado: (2007)

Left ventricular hemodynamic forces are altered in patients with dilated cardiomyopathy
por: Eriksson, Jonatan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_tbtelb86ojng3pipejg2acugdi