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Sphingosine 1-Phosphate Activation of EGFR As a Novel Target for Meningitic Escherichia coli Penetration of the Blood-Brain Barrier

Central nervous system (CNS) infection continues to be an important cause of mortality and morbidity, necessitating new approaches for investigating its pathogenesis, prevention and therapy. Escherichia coli is the most common Gram-negative bacillary organism causing meningitis, which develops follo...

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Detalles Bibliográficos
Autores principales: Wang, Xiangru, Maruvada, Ravi, Morris, Andrew J., Liu, Jun O., Wolfgang, Michael J., Baek, Dong Jae, Bittman, Robert, Kim, Kwang Sik
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053521/
https://www.ncbi.nlm.nih.gov/pubmed/27711202
http://dx.doi.org/10.1371/journal.ppat.1005926

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