Hemizygous Deletion on Chromosome 3p26.1 Is Associated with Heavy Smoking among African American Subjects in the COPDGene Study

Many well-powered genome-wide association studies have identified genetic determinants of self-reported smoking behaviors and measures of nicotine dependence, but most have not considered the role of structural variants, such as copy number variation (CNVs), influencing these phenotypes. Here, we in...

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Detalles Bibliográficos
Autores principales: Begum, Ferdouse, Ruczinski, Ingo, Hokanson, John E., Lutz, Sharon M., Parker, Margaret M., Cho, Michael H., Hetmanski, Jacqueline B., Scharpf, Robert B., Crapo, James D., Silverman, Edwin K., Beaty, Terri H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2016
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053531/
https://www.ncbi.nlm.nih.gov/pubmed/27711239
http://dx.doi.org/10.1371/journal.pone.0164134

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