Cargando…

Stability of the hybrid epithelial/mesenchymal phenotype

Epithelial-to-Mesenchymal Transition (EMT) and its reverse – Mesenchymal to Epithelial Transition (MET) – are hallmarks of cellular plasticity during embryonic development and cancer metastasis. During EMT, epithelial cells lose cell-cell adhesion and gain migratory and invasive traits either partia...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jolly, Mohit Kumar, Tripathi, Satyendra C., Jia, Dongya, Mooney, Steven M., Celiktas, Muge, Hanash, Samir M., Mani, Sendurai A., Pienta, Kenneth J., Ben-Jacob, Eshel, Levine, Herbert
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053633/ https://www.ncbi.nlm.nih.gov/pubmed/27008704 http://dx.doi.org/10.18632/oncotarget.8166

Ejemplares similares

OVOL guides the epithelial-hybrid-mesenchymal transition
por: Jia, Dongya, et al.
Publicado: (2015)

Distinguishing mechanisms underlying EMT tristability
por: Jia, Dongya, et al.
Publicado: (2017)

Coupling the modules of EMT and stemness: A tunable ‘stemness window’ model
por: Jolly, Mohit Kumar, et al.
Publicado: (2015)

Implications of the Hybrid Epithelial/Mesenchymal Phenotype in Metastasis
por: Jolly, Mohit Kumar, et al.
Publicado: (2015)

Epithelial/mesenchymal plasticity: how have quantitative mathematical models helped improve our understanding?
por: Jolly, Mohit Kumar, et al.
Publicado: (2017)

NFATc Acts as a Non-Canonical Phenotypic Stability Factor for a Hybrid Epithelial/Mesenchymal Phenotype
por: Subbalakshmi, Ayalur Raghu, et al.
Publicado: (2020)

Notch-Jagged signalling can give rise to clusters of cells exhibiting a hybrid epithelial/mesenchymal phenotype
por: Boareto, Marcelo, et al.
Publicado: (2016)

NRF2 activates a partial epithelial-mesenchymal transition and is maximally present in a hybrid epithelial/mesenchymal phenotype
por: Bocci, Federico, et al.
Publicado: (2019)

Numb prevents a complete epithelial–mesenchymal transition by modulating Notch signalling
por: Bocci, Federico, et al.
Publicado: (2017)

Interconnected feedback loops among ESRP1, HAS2, and CD44 regulate epithelial-mesenchymal plasticity in cancer
por: Jolly, Mohit Kumar, et al.
Publicado: (2018)

Editorial: Characterizing the Multi-Faceted Dynamics of Tumor Cell Plasticity
por: Tripathi, Satyendra Chandra, et al.
Publicado: (2021)

Comparative Study of Transcriptomics-Based Scoring Metrics for the Epithelial-Hybrid-Mesenchymal Spectrum
por: Chakraborty, Priyanka, et al.
Publicado: (2020)

Quantifying Cancer Epithelial-Mesenchymal Plasticity and its Association with Stemness and Immune Response
por: Jia, Dongya, et al.
Publicado: (2019)

NRF2-dependent Epigenetic Regulation can Promote the Hybrid Epithelial/Mesenchymal Phenotype
por: Jia, Wen, et al.
Publicado: (2022)

A mechanism for epithelial-mesenchymal heterogeneity in a population of cancer cells
por: Tripathi, Shubham, et al.
Publicado: (2020)

Immunosuppressive Traits of the Hybrid Epithelial/Mesenchymal Phenotype
por: Sahoo, Sarthak, et al.
Publicado: (2021)

Gene expression profiles of inflammatory breast cancer reveal high heterogeneity across the epithelial-hybrid-mesenchymal spectrum
por: Chakraborty, Priyanka, et al.
Publicado: (2021)

Quantifying the Patterns of Metabolic Plasticity and Heterogeneity along the Epithelial–Hybrid–Mesenchymal Spectrum in Cancer
por: Muralidharan, Srinath, et al.
Publicado: (2022)

Transcriptomic-Based Quantification of the Epithelial-Hybrid-Mesenchymal Spectrum across Biological Contexts
por: Mandal, Susmita, et al.
Publicado: (2021)

The three-way switch operation of Rac1/RhoA GTPase-based circuit controlling amoeboid-hybrid-mesenchymal transition
por: Huang, Bin, et al.
Publicado: (2014)

A Theoretical Approach to Coupling the Epithelial-Mesenchymal Transition (EMT) to Extracellular Matrix (ECM) Stiffness via LOXL2
por: Deng, Youyuan, et al.
Publicado: (2021)

Nrf2 Modulates the Hybrid Epithelial/Mesenchymal Phenotype and Notch Signaling During Collective Cancer Migration
por: Vilchez Mercedes, Samuel A., et al.
Publicado: (2022)

Phenotypic Plasticity and Cell Fate Decisions in Cancer: Insights from Dynamical Systems Theory
por: Jia, Dongya, et al.
Publicado: (2017)

Decoding the coupled decision-making of the epithelial-mesenchymal transition and metabolic reprogramming in cancer
por: Galbraith, Madeline, et al.
Publicado: (2022)

Network topology metrics explaining enrichment of hybrid epithelial/mesenchymal phenotypes in metastasis
por: Rashid, Mubasher, et al.
Publicado: (2022)

Computational Modeling of the Crosstalk Between Macrophage Polarization and Tumor Cell Plasticity in the Tumor Microenvironment
por: Li, Xuefei, et al.
Publicado: (2019)

A mechanism-based computational model to capture the interconnections among epithelial-mesenchymal transition, cancer stem cells and Notch-Jagged signaling
por: Bocci, Federico, et al.
Publicado: (2018)

Mapping phenotypic heterogeneity in melanoma onto the epithelial-hybrid-mesenchymal axis
por: Pillai, Maalavika, et al.
Publicado: (2022)

Interrogating the topological robustness of gene regulatory circuits by randomization
por: Huang, Bin, et al.
Publicado: (2017)

Identification of EMT signaling cross-talk and gene regulatory networks by single-cell RNA sequencing
por: Deshmukh, Abhijeet P., et al.
Publicado: (2021)

Dual role of CASP8AP2/FLASH in regulating epithelial-to-mesenchymal transition plasticity (EMP)
por: Catalanotto, Madison, et al.
Publicado: (2023)

Tumor Budding: The Name is EMT. Partial EMT.
por: Grigore, Alexandru Dan, et al.
Publicado: (2016)

Phenotypic plasticity in prostate cancer: role of intrinsically disordered proteins
por: Mooney, Steven M, et al.
Publicado: (2016)

Breast cancer dormancy: need for clinically relevant models to address current gaps in knowledge
por: Bushnell, Grace G., et al.
Publicado: (2021)

Investigating the Link between Molecular Subtypes of Glioblastoma, Epithelial-Mesenchymal Transition, and CD133 Cell Surface Protein
por: Zarkoob, Hadi, et al.
Publicado: (2013)

Epithelial-to-Mesenchymal Plasticity in Circulating Tumor Cell Lines Sequentially Derived from a Patient with Colorectal Cancer
por: Balcik-Ercin, Pelin, et al.
Publicado: (2021)

Population Dynamics of Epithelial-Mesenchymal Heterogeneity in Cancer Cells
por: Jain, Paras, et al.
Publicado: (2022)

Epithelial-mesenchymal transition and cancer stem cells: a dangerously dynamic duo in breast cancer progression
por: May, Caitlin D, et al.
Publicado: (2011)

Insights into the Multi-Dimensional Dynamic Landscape of Epithelial–Mesenchymal Plasticity through Inter-Disciplinary Approaches
por: Kumar Jolly, Mohit, et al.
Publicado: (2020)

Phenotypic Heterogeneity of Triple-Negative Breast Cancer Mediated by Epithelial–Mesenchymal Plasticity
por: Kvokačková, Barbora, et al.
Publicado: (2021)

Cannot write session to /tmp/vufind_sessions/sess_4uhmba1d6lv791d3d5ejorm43v