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The degree of intratumor mutational heterogeneity varies by primary tumor sub-site
In an era where mutational profiles inform treatment options, it is critical to know the extent to which tumor biopsies represent the molecular profile of the primary and metastatic tumor. Head and neck squamous cell carcinoma (HNSCC) arise primarily in the mucosal lining of oral cavity and orophary...
Autores principales: | Ledgerwood, Levi G., Kumar, Dhruv, Eterovic, Agda Karina, Wick, Jo, Chen, Ken, Zhao, Hao, Tazi, Loubna, Manna, Pradip, Kerley, Spencer, Joshi, Radhika, Wang, Lin, Chiosea, Simion I., Garnett, James David, Tsue, Terance Ted, Chien, Jeremy, Mills, Gordon B., Grandis, Jennifer Rubin, Thomas, Sufi Mary |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053641/ https://www.ncbi.nlm.nih.gov/pubmed/27034009 http://dx.doi.org/10.18632/oncotarget.8448 |
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