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Human papillomavirus oncogenic E6 protein regulates human β-defensin 3 (hBD3) expression via the tumor suppressor protein p53

Human β-defensin-3 (hBD3) is an epithelial cell-derived innate immune regulatory molecule overexpressed in oral dysplastic lesions and fosters a tumor-promoting microenvironment. Expression of hBD3 is induced by the epidermal growth factor receptor signaling pathway. Here we describe a novel pathway...

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Detalles Bibliográficos
Autores principales:	DasGupta, Twishasri, Nweze, Emeka I., Yue, Hong, Wang, Liming, Jin, Jessica, Ghosh, Santosh K., Kawsar, Hameem I., Zender, Chad, Androphy, Elliot J., Weinberg, Aaron, McCormick, Thomas S., Jin, Ge
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053661/ https://www.ncbi.nlm.nih.gov/pubmed/27034006 http://dx.doi.org/10.18632/oncotarget.8443

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