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Gap junction-mediated transfer of miR-145-5p from microvascular endothelial cells to colon cancer cells inhibits angiogenesis

Gap junctional communication between cancer cells and blood capillary cells is crucial to tumor growth and invasion. Gap junctions may transfer microRNAs (miRs) among cells. Here, we explore the impact of such a transfer in co-culture assays, using the antitumor miR-145 as an example. The SW480 colo...

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Detalles Bibliográficos
Autores principales: Thuringer, Dominique, Jego, Gaetan, Berthenet, Kevin, Hammann, Arlette, Solary, Eric, Garrido, Carmen
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053717/
https://www.ncbi.nlm.nih.gov/pubmed/27058413
http://dx.doi.org/10.18632/oncotarget.8583