Medulloblastoma-associated DDX3 variant selectively alters the translational response to stress

DDX3X encodes a DEAD-box family RNA helicase (DDX3) commonly mutated in medulloblastoma, a highly aggressive cerebellar tumor affecting both children and adults. Despite being implicated in several facets of RNA metabolism, the nature and scope of DDX3′s interactions with RNA remain unclear. Here, w...

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Detalles Bibliográficos
Autores principales: Oh, Sekyung, Flynn, Ryan A., Floor, Stephen N., Purzner, James, Martin, Lance, Do, Brian T., Schubert, Simone, Vaka, Dedeepya, Morrissy, Sorana, Li, Yisu, Kool, Marcel, Hovestadt, Volker, Jones, David T.W., Northcott, Paul A., Risch, Thomas, Warnatz, Hans-Jörg, Yaspo, Marie-Laure, Adams, Christopher M., Leib, Ryan D., Breese, Marcus, Marra, Marco A., Malkin, David, Lichter, Peter, Doudna, Jennifer A., Pfister, Stefan M., Taylor, Michael D., Chang, Howard Y., Cho, Yoon-Jae
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053718/
https://www.ncbi.nlm.nih.gov/pubmed/27058758
http://dx.doi.org/10.18632/oncotarget.8612

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053718/
https://www.ncbi.nlm.nih.gov/pubmed/27058758
http://dx.doi.org/10.18632/oncotarget.8612

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