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Hypoxia primes human normal prostate epithelial cells and cancer cell lines for the NLRP3 and AIM2 inflammasome activation

The molecular mechanisms by which hypoxia contributes to prostatic chronic inflammation (PCI) remain largely unknown. Because hypoxia stimulates the transcriptional activity of NF-κB, which “primes” cells for inflammasome activation by inducing the expression of NLRP3 or AIM2 receptor and pro-IL-1β,...

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Detalles Bibliográficos
Autores principales:	Panchanathan, Ravichandran, Liu, Hongzhu, Choubey, Divaker
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053719/ https://www.ncbi.nlm.nih.gov/pubmed/27058421 http://dx.doi.org/10.18632/oncotarget.8594

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