Cargando…

Metformin represses bladder cancer progression by inhibiting stem cell repopulation via COX2/PGE2/STAT3 axis

Cancer stem cells (CSCs) are a sub-population of tumor cells playing essential roles in initiation, differentiation, recurrence, metastasis and development of drug resistance of various cancers, including bladder cancer. Although multiple lines of evidence suggest that metformin is capable of repres...

Descripción completa

Detalles Bibliográficos
Autores principales: Liu, Qiuli, Yuan, Wenqiang, Tong, Dali, Liu, Gaolei, Lan, Weihua, Zhang, Dianzheng, Xiao, Hualiang, Zhang, Yao, Huang, Zaoming, Yang, Junjie, Zhang, Jun, Jiang, Jun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053723/
https://www.ncbi.nlm.nih.gov/pubmed/27058422
http://dx.doi.org/10.18632/oncotarget.8595