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A new role of the Rac-GAP β2-chimaerin in cell adhesion reveals opposite functions in breast cancer initiation and tumor progression

β2-chimaerin is a Rac1-specific negative regulator and a candidate tumor suppressor in breast cancer but its precise function in mammary tumorigenesis in vivo is unknown. Here, we study for the first time the role of β2-chimaerin in breast cancer using a mouse model and describe an unforeseen role f...

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Detalles Bibliográficos
Autores principales:	Casado-Medrano, Victoria, Barrio-Real, Laura, García-Rostán, Ginesa, Baumann, Matti, Rocks, Oliver, Caloca, María J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053728/ https://www.ncbi.nlm.nih.gov/pubmed/27058424 http://dx.doi.org/10.18632/oncotarget.8597

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