Dual oncogenic and tumor suppressor roles of the promyelocytic leukemia gene in hepatocarcinogenesis associated with hepatitis B virus surface antigen

Proteasome-mediated degradation of promyelocytic leukemia tumor suppressor (PML) is upregulated in many viral infections and cancers. We previously showed that PML knockdown promotes early-onset hepatocellular carcinoma (HCC) in hepatitis B virus surface antigen (HBsAg)-transgenic mice. Here we repo...

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Detalles Bibliográficos
Autores principales: Chung, Yih-Lin, Wu, Mei-Ling
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053734/
https://www.ncbi.nlm.nih.gov/pubmed/27058621
http://dx.doi.org/10.18632/oncotarget.8613

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053734/
https://www.ncbi.nlm.nih.gov/pubmed/27058621
http://dx.doi.org/10.18632/oncotarget.8613

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