Cargando…

Prospective validation of microRNA signatures for detecting pancreatic malignant transformation in endoscopic-ultrasound guided fine-needle aspiration biopsies

BACKGROUND: Pancreatic ductal adenocarcinoma (PDAC) is a lethal disease. Novel biomarkers are required to aid treatment decisions and improve patient outcomes. MicroRNAs (miRNAs) are potentially ideal diagnostic biomarkers, as they are stable molecules, and tumour and tissue specific. RESULTS: Logis...

Descripción completa

Detalles Bibliográficos
Autores principales:	Frampton, Adam E., Krell, Jonathan, Prado, Mireia Mato, Gall, Tamara M.H., Abbassi-Ghadi, Nima, Del Vecchio Blanco, Giovanna, Funel, Niccola, Giovannetti, Elisa, Castellano, Leandro, Basyouny, Mohamed, Habib, Nagy A., Kaltsidis, Harry, Vlavianos, Panagiotis, Stebbing, Justin, Jiao, Long R.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Impact Journals LLC 2016
Materias:	Research Paper
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053745/ https://www.ncbi.nlm.nih.gov/pubmed/27086919 http://dx.doi.org/10.18632/oncotarget.8699

Ejemplares similares

Glypican-1 is enriched in circulating-exosomes in pancreatic cancer and correlates with tumor burden
por: Frampton, Adam E., et al.
Publicado: (2018)

MicroRNAs Targeting Oncogenes Are Down-Regulated in Pancreatic Malignant Transformation from Benign Tumors
por: Jiao, Long R., et al.
Publicado: (2012)

A bile-based microRNA signature for differentiating malignant from benign pancreaticobiliary disease
por: Mato Prado, Mireia, et al.
Publicado: (2023)

TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
por: Ottaviani, Silvia, et al.
Publicado: (2018)

Author Correction: TGF-β induces miR-100 and miR-125b but blocks let-7a through LIN28B controlling PDAC progression
por: Ottaviani, Silvia, et al.
Publicado: (2019)

Sustained expression of miR-26a promotes chromosomal instability and tumorigenesis through regulation of CHFR
por: Castellano, Leandro, et al.
Publicado: (2017)

Can we predict long-term survival in resectable pancreatic ductal adenocarcinoma?
por: Gall, Tamara M.H., et al.
Publicado: (2019)

The clinical significance of tumor infiltrating lymphoctyes in breast cancer: does subtype matter?
por: Krell, Jonathan, et al.
Publicado: (2012)

MicroRNA profiling of primary pulmonary enteric adenocarcinoma in members from the same family reveals some similarities to pancreatic adenocarcinoma—a step towards personalized therapy
por: Garajová, Ingrid, et al.
Publicado: (2015)

Galectin-4 expression is associated with reduced lymph node metastasis and modulation of Wnt/β-catenin signalling in pancreatic adenocarcinoma
por: Maftouh, Mina, et al.
Publicado: (2014)

TP53 regulates miRNA association with AGO2 to remodel the miRNA–mRNA interaction network
por: Krell, Jonathan, et al.
Publicado: (2016)

Deep sequencing of small RNAs identifies canonical and non-canonical miRNA and endogenous siRNAs in mammalian somatic tissues
por: Castellano, Leandro, et al.
Publicado: (2013)

Pancreatic Cancer
por: Funel, Niccola, et al.
Publicado: (2015)

Development of bioluminescent chick chorioallantoic membrane (CAM) models for primary pancreatic cancer cells: a platform for drug testing
por: Rovithi, Maria, et al.
Publicado: (2017)

Growth Arrest-Specific Transcript 5 Associated snoRNA Levels Are Related to p53 Expression and DNA Damage in Colorectal Cancer
por: Krell, Jonathan, et al.
Publicado: (2014)

Seldinger method for intraoperative cholangiography: a practical approach
por: Abbassi-Ghadi, N, et al.
Publicado: (2012)

Mutational Profiling of Kinases in Human Tumours of Pancreatic Origin Identifies Candidate Cancer Genes in Ductal and Ampulla of Vater Carcinomas
por: Corbo, Vincenzo, et al.
Publicado: (2010)

AKT1 and SELP Polymorphisms Predict the Risk of Developing Cachexia in Pancreatic Cancer Patients
por: Avan, Abolfazl, et al.
Publicado: (2014)

miR‐515‐5p controls cancer cell migration through MARK4 regulation
por: Pardo, Olivier E, et al.
Publicado: (2016)

The germline of the malaria mosquito produces abundant miRNAs, endo-siRNAs, piRNAs and 29-nt small RNAs
por: Castellano, Leandro, et al.
Publicado: (2015)

3-(6-Phenylimidazo [2,1-b][1,3,4]thiadiazol-2-yl)-1H-Indole Derivatives as New Anticancer Agents in the Treatment of Pancreatic Ductal Adenocarcinoma
por: Cascioferro, Stella, et al.
Publicado: (2020)

Triticum vulgare Extract Modulates Protein-Kinase B and Matrix Metalloproteinases 9 Protein Expression in BV-2 Cells: Bioactivity on Inflammatory Pathway Associated with Molecular Mechanism Wound Healing
por: Funel, Niccola, et al.
Publicado: (2020)

Pancreatic serous cystoadenoma (CSA) showing increased tracer uptake at 68-GaDOTA-peptide Positron Emission Tomography (68Ga-DOTA-peptide PET-CT): a case report
por: Nappo, Gennaro, et al.
Publicado: (2020)

Ampullary Cancer: Histological Subtypes, Markers, and Clinical Behaviour—State of the Art and Perspectives
por: Nappo, Gennaro, et al.
Publicado: (2023)

Fine Needle Aspiration
por: Wiwanitkit, Viroj
Publicado: (2014)

Myocardial MiR-30 downregulation triggered by doxorubicin drives alterations in β-adrenergic signaling and enhances apoptosis
por: Roca-Alonso, L, et al.
Publicado: (2015)

miR-23b regulates cytoskeletal remodeling, motility and metastasis by directly targeting multiple transcripts
por: Pellegrino, Loredana, et al.
Publicado: (2013)

Leptin induces upregulation of sphingosine kinase 1 in oestrogen receptor-negative breast cancer via Src family kinase-mediated, janus kinase 2-independent pathway
por: Alshaker, Heba, et al.
Publicado: (2014)

Mapping Local Cytosolic Enzymatic Activity in Human Esophageal Mucosa with Porous Silicon Nanoneedles
por: Chiappini, Ciro, et al.
Publicado: (2015)

Phospho-Akt overexpression is prognostic and can be used to tailor the synergistic interaction of Akt inhibitors with gemcitabine in pancreatic cancer
por: Massihnia, Daniela, et al.
Publicado: (2017)

Positive Outcomes in a Virtual Partial Hospitalization Program
por: Vlavianos, Theodore, et al.
Publicado: (2022)

Role of Fine Needle Aspiration Cytology in Diagnosis of Solitary Thyroid Nodules
por: I Wahid, Fazal, et al.
Publicado: (2011)

Breast Cancer in the Setting of HIV
por: Palan, Mitul, et al.
Publicado: (2011)

Differential diagnosis of thyroid nodules using fine-needle aspiration cytology and oncogene mutation screening: are we ready?
por: Melillo, Rosa Marina, et al.
Publicado: (2010)

Role of c-MET Inhibitors in Overcoming Drug Resistance in Spheroid Models of Primary Human Pancreatic Cancer and Stellate Cells
por: Firuzi, Omidreza, et al.
Publicado: (2019)

Unravelling the Diagnostic Dilemma: A MicroRNA Panel of Circulating MiR-16 and MiR-877 as A Diagnostic Classifier for Distal Bile Duct Tumors
por: Meijer, Laura L., et al.
Publicado: (2019)

Transbronchial needle aspiration “by the books”
por: Kupeli, Elif, et al.
Publicado: (2011)

In Reply to: Fine Needle Aspiration
por: Ehsanbakhsh, Ali-Reza, et al.
Publicado: (2014)

The Efficacy of Lapatinib in Metastatic Breast Cancer with HER2 Non-Amplified Primary Tumors and EGFR Positive Circulating Tumor Cells: A Proof-Of-Concept Study
por: Stebbing, Justin, et al.
Publicado: (2013)

Diagnostic accuracy of ultrasound and fine‐needle aspiration in the study of thyroid nodule and multinodular goitre
por: Rabal Fueyo, Antonio, et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_as26dk2js44494c1e1gibbrsfd