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Serum miR-125b is a non-invasive predictive biomarker of the pre-operative chemoradiotherapy responsiveness in patients with rectal adenocarcinoma
BACKGROUND: Therapeutic management of Locally Advanced Rectal Cancer (LARC) involves pre-operative chemoradiotherapy (pCRT) followed by surgery. However, after pCRT the complete pathological response is approximately 20%, whereas in 20 to 40% of patients the response is poor or absent. METHODS: Canc...
Autores principales: | D'Angelo, Edoardo, Fassan, Matteo, Maretto, Isacco, Pucciarelli, Salvatore, Zanon, Carlo, Digito, Maura, Rugge, Massimo, Nitti, Donato, Agostini, Marco |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Impact Journals LLC
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053752/ https://www.ncbi.nlm.nih.gov/pubmed/27081702 http://dx.doi.org/10.18632/oncotarget.8725 |
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