Transcriptome–metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals network level interactions in toxicologic mechanism

A combination of the herbicide paraquat (PQ) and fungicide maneb (MB) has been linked to Parkinson's disease. Previous studies show that this involves an additive toxicity with at least two different mechanisms. However, detailed understanding of mixtures is often difficult to elucidate because...

Descripción completa

Detalles Bibliográficos
Autores principales: Roede, James R., Uppal, Karan, Park, Youngja, Tran, ViLinh, Jones, Dean P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2014
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053767/
https://www.ncbi.nlm.nih.gov/pubmed/27722094
http://dx.doi.org/10.1016/j.toxrep.2014.07.006

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053767/
https://www.ncbi.nlm.nih.gov/pubmed/27722094
http://dx.doi.org/10.1016/j.toxrep.2014.07.006

Ejemplares similares