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Transcriptome–metabolome wide association study (TMWAS) of maneb and paraquat neurotoxicity reveals network level interactions in toxicologic mechanism
A combination of the herbicide paraquat (PQ) and fungicide maneb (MB) has been linked to Parkinson's disease. Previous studies show that this involves an additive toxicity with at least two different mechanisms. However, detailed understanding of mixtures is often difficult to elucidate because...
Autores principales: | Roede, James R., Uppal, Karan, Park, Youngja, Tran, ViLinh, Jones, Dean P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2014
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053767/ https://www.ncbi.nlm.nih.gov/pubmed/27722094 http://dx.doi.org/10.1016/j.toxrep.2014.07.006 |
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