Hypothalamic transcriptomes of 99 mouse strains reveal trans eQTL hotspots, splicing QTLs and novel non-coding genes

Previous studies had shown that the integration of genome wide expression profiles, in metabolic tissues, with genetic and phenotypic variance, provided valuable insight into the underlying molecular mechanisms. We used RNA-Seq to characterize hypothalamic transcriptome in 99 inbred strains of mice...

Descripción completa

Detalles Bibliográficos
Autores principales: Hasin-Brumshtein, Yehudit, Khan, Arshad H, Hormozdiari, Farhad, Pan, Calvin, Parks, Brian W, Petyuk, Vladislav A, Piehowski, Paul D, Brümmer, Anneke, Pellegrini, Matteo, Xiao, Xinshu, Eskin, Eleazar, Smith, Richard D, Lusis, Aldons J, Smith, Desmond J
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2016
Materias:
Genomics and Evolutionary Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053804/
https://www.ncbi.nlm.nih.gov/pubmed/27623010
http://dx.doi.org/10.7554/eLife.15614

Ejemplares similares

Ejemplares similares