Sphingosine-1-phosphate receptor-1 (S1P(1)) is expressed by lymphocytes, dendritic cells, and endothelium and modulated during inflammatory bowel disease

The sphingosine-1-phosphate receptor-1 (S1P(1)) agonist ozanimod ameliorates ulcerative colitis, yet its mechanism of action is unknown. Here we examine the cell subsets that express S1P(1) in intestine using S1P(1)-eGFP mice, the regulation of S1P(1) expression in lymphocytes after administration o...

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Detalles Bibliográficos
Autores principales: Karuppuchamy, Thangaraj, Behrens, En-hui, González-Cabrera, Pedro, Sarkisyan, Gor, Gima, Lauren, Boyer, Joshua D., Bamias, Giorgos, Jedlicka, Paul, Veny, Marisol, Clark, David, Peach, Robert, Scott, Fiona, Rosen, Hugh, Rivera-Nieves, Jesús
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053832/
https://www.ncbi.nlm.nih.gov/pubmed/27049060
http://dx.doi.org/10.1038/mi.2016.35

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