Cargando…
Anti-tumor effects of perphenazine on canine lymphoma
Lymphoma is one of the most common malignant tumors in canine. Protein phosphatase 2A (PP2A), a well-conserved serine/threonine phosphatase, plays a critical role as a tumor suppressor. Perphenazine (PPZ) is one of the phenothiazines and widely used as an antipsychotic drug. Recently, it is reported...
Autores principales: | TSUJI, Shunya, YABE, Ryotaro, USUI, Tatsuya, MIZUNO, Takuya, OHAMA, Takashi, SATO, Koichi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Japanese Society of Veterinary Science
2016
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053930/ https://www.ncbi.nlm.nih.gov/pubmed/27150024 http://dx.doi.org/10.1292/jvms.15-0707 |
Ejemplares similares
-
The therapeutic effects of SET/I2PP2A inhibitors on canine
melanoma
por: ENJOJI, Shuhei, et al.
Publicado: (2015) -
Perphenazine exerts antitumor effects on HUT78 cells through Akt dephosphorylation by protein phosphatase 2A
por: Tsuji, Shunya, et al.
Publicado: (2021) -
Characterization of SET/I2PP2A Isoforms in Dogs
por: YABE, Ryotaro, et al.
Publicado: (2014) -
Efficacy of an anti-cancer strategy targeting SET in canine
osteosarcoma
por: TSUJI, Shunya, et al.
Publicado: (2019) -
A stable association with PME‐1 may be dispensable for PP2A demethylation – implications for the detection of PP2A methylation and immunoprecipitation
por: Yabe, Ryotaro, et al.
Publicado: (2018)