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Sustained delivery of recombinant human bone morphogenetic protein-2 from perlecan domain I - functionalized electrospun poly (ε-caprolactone) scaffolds for bone regeneration
BACKGROUND: Biomaterial scaffolds that deliver growth factors such as recombinant human bone morphogenetic proteins-2 (rhBMP-2) have improved clinical bone tissue engineering by enhancing bone tissue regeneration. This approach could be further improved if the controlled delivery of bioactive rhBMP-...
Autores principales: | Chiu, Yu-Chieh, Fong, Eliza L., Grindel, Brian J., Kasper, Fred K., Harrington, Daniel A., Farach-Carson, Mary C. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer Berlin Heidelberg
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053971/ https://www.ncbi.nlm.nih.gov/pubmed/27714703 http://dx.doi.org/10.1186/s40634-016-0057-1 |
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