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C9orf72’s Interaction with Rab GTPases—Modulation of Membrane Traffic and Autophagy

Hexanucleotide repeat expansion in an intron of Chromosome 9 open reading frame 72 (C9orf72) is the most common genetic cause of Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Dementia (FTD). While functional haploinsufficiency of C9orf72 resulting from the mutation may play a role in ALS/FT...

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Detalles Bibliográficos
Autor principal:	Tang, Bor L.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5053994/ https://www.ncbi.nlm.nih.gov/pubmed/27774051 http://dx.doi.org/10.3389/fncel.2016.00228

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