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Regulation of mRNA Translation by MID1: A Common Mechanism of Expanded CAG Repeat RNAs

Expansion of CAG repeats, which code for the disease-causing polyglutamine protein, is a common feature in polyglutamine diseases. RNA-mediated mechanisms that contribute to neuropathology in polyglutamine diseases are important. RNA-toxicity describes a phenomenon by which the mutant CAG repeat RNA...

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Detalles Bibliográficos
Autores principales:	Griesche, Nadine, Schilling, Judith, Weber, Stephanie, Rohm, Marlena, Pesch, Verena, Matthes, Frank, Auburger, Georg, Krauss, Sybille
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2016
Materias:	Neuroscience
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054010/ https://www.ncbi.nlm.nih.gov/pubmed/27774050 http://dx.doi.org/10.3389/fncel.2016.00226

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