Cargando…
A method for predicting individual residue contributions to enzyme specificity and binding-site energies, and its application to MTH1
A new method for predicting the energy contributions to substrate binding and to specificity has been developed. Conventional global optimization methods do not permit the subtle effects responsible for these properties to be modeled with sufficient precision to allow confidence to be placed in the...
| Autor principal: | |
|---|---|
| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2016
|
| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054044/ https://www.ncbi.nlm.nih.gov/pubmed/27714533 http://dx.doi.org/10.1007/s00894-016-3119-5 |