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Reduction of Isoagglutinin in Intravenous Immunoglobulin (IVIG) Using Blood Group A- and B-Specific Immunoaffinity Chromatography: Industry-Scale Assessment

BACKGROUND: Hemolysis, a rare but potentially serious complication of intravenous immunoglobulin (IVIG) therapy, is associated with the presence of antibodies to blood groups A and B (isoagglutinins) in the IVIG product. An immunoaffinity chromatography (IAC) step in the production process could dec...

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Detalles Bibliográficos
Autores principales:	Gerber, Simon, Gaida, Annette, Spiegl, Nicole, Wymann, Sandra, Antunes, Adriano Marques, Menyawi, Ibrahim El, Zurbriggen, Brigitte, Hubsch, Alphonse, Imboden, Martin
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer International Publishing 2016
Materias:	Original Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054059/ https://www.ncbi.nlm.nih.gov/pubmed/27646589 http://dx.doi.org/10.1007/s40259-016-0192-3

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