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Identification of Conserved Regulatory Elements in Mammalian Promoter Regions: A Case Study Using the PCK1 Promoter

A systematic phylogenetic footprinting approach was performed to identify conserved transcription factor binding sites (TFBSs) in mammalian promoter regions using human, mouse and rat sequence alignments. We found that the score distributions of most binding site models did not follow the Gaussian d...

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Detalles Bibliográficos
Autores principales:	Liu, George E., Weirauch, Matthew T., Van Tassell, Curtis P., Li, Robert W., Sonstegard, Tad S., Matukumalli, Lakshmi K., Connor, Erin E., Hanson, Richard W., Yang, Jianqi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2008
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054123/ https://www.ncbi.nlm.nih.gov/pubmed/19329064 http://dx.doi.org/10.1016/S1672-0229(09)60001-2

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