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HMG-CoAR expression in male breast cancer: relationship with hormone receptors, Hippo transducers and survival outcomes
Male breast cancer (MBC) is a rare hormone-driven disease often associated with obesity. HMG-CoAR is the central enzyme of the mevalonate pathway, a molecular route deputed to produce cholesterol and steroid-based hormones. HMG-CoAR regulates the oncogenic Hippo transducers TAZ/YAP whose expression...
Autores principales: | Di Benedetto, Anna, Mottolese, Marcella, Sperati, Francesca, Ercolani, Cristiana, Di Lauro, Luigi, Pizzuti, Laura, Vici, Patrizia, Terrenato, Irene, Shaaban, Abeer M., Sundara-Rajan, Sreekumar, Humphries, Matthew P., Barba, Maddalena, Speirs, Valerie, De Maria, Ruggero, Maugeri-Saccà, Marcello |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2016
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054365/ https://www.ncbi.nlm.nih.gov/pubmed/27713571 http://dx.doi.org/10.1038/srep35121 |
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