Increasing the Efficiency of CRISPR/Cas9-mediated Precise Genome Editing of HSV-1 Virus in Human Cells

Genetically modified HSV-1 viruses serve as promising vectors for tumour therapy and vaccine development. The CRISPR/Cas9 system is one of the most powerful tools for precise gene editing of the genomes of organisms. However, whether the CRISPR/Cas9 system can precisely and efficiently make gene rep...

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Detalles Bibliográficos
Autores principales: Lin, Chaolong, Li, Huanhuan, Hao, Mengru, Xiong, Dan, Luo, Yong, Huang, Chenghao, Yuan, Quan, Zhang, Jun, Xia, Ningshao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054376/
https://www.ncbi.nlm.nih.gov/pubmed/27713537
http://dx.doi.org/10.1038/srep34531

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