Versatile members of the DNAJ family show Hsp70 dependent anti-aggregation activity on RING1 mutant parkin C289G

Parkinson’s disease is one of the most common neurodegenerative disorders and several mutations in different genes have been identified to contribute to the disease. A loss of function parkin RING1 domain mutant (C289G) is associated with autosomal-recessive juvenile-onset Parkinsonism (AR-JP) and d...

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Detalles Bibliográficos
Autores principales: Kakkar, Vaishali, Kuiper, E. F. Elsiena, Pandey, Abhinav, Braakman, Ineke, Kampinga, Harm H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2016
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054386/
https://www.ncbi.nlm.nih.gov/pubmed/27713507
http://dx.doi.org/10.1038/srep34830

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054386/
https://www.ncbi.nlm.nih.gov/pubmed/27713507
http://dx.doi.org/10.1038/srep34830

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