PBOND: Web Server for the Prediction of Proline and Non-Proline cis/trans Isomerization

PBOND is a web server that predicts the conformation of the peptide bond between any two amino acids. PBOND classifies the peptide bonds into one out of four classes, namely cis imide (cis-Pro), cis amide (cis-nonPro), trans imide (trans-Pro) and trans amide (trans-nonPro). Moreover, for every predi...

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Detalles Bibliográficos
Autores principales: Exarchos, Konstantinos P., Exarchos, Themis P., Papaloukas, Costas, Troganis, Anastassios N., Fotiadis, Dimitrios I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2009
Materias:
Application Note
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054403/
https://www.ncbi.nlm.nih.gov/pubmed/19944386
http://dx.doi.org/10.1016/S1672-0229(08)60042-X
Descripción
Sumario:PBOND is a web server that predicts the conformation of the peptide bond between any two amino acids. PBOND classifies the peptide bonds into one out of four classes, namely cis imide (cis-Pro), cis amide (cis-nonPro), trans imide (trans-Pro) and trans amide (trans-nonPro). Moreover, for every prediction a reliability index is computed. The underlying structure of the server consists of three stages: (1) feature extraction, (2) feature selection and (3) peptide bond classification. PBOND can handle both single sequences as well as multiple sequences for batch processing. The predictions can either be directly downloaded from the web site or returned via e-mail. The PBOND web server is freely available at http://195.251.198.21/pbond.html.

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