The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report

Abnormal uterine bleeding in a patient on maintenance hormonal therapy for breast cancer should raise concern for endometrial abnormalities including rare uterine metastasis from the breast. Hormonal receptor profile changes in metastatic lesions favoring human epidermal growth factor receptor 2 (HE...

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Detalles Bibliográficos
Autores principales: Moey, Melissa Y. Y., Hassan, Omer A., Papageorgiou, Christos N., Schnepp, Stephanie L., Hoff, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054465/
https://www.ncbi.nlm.nih.gov/pubmed/27761241
http://dx.doi.org/10.1002/ccr3.602
Descripción
Sumario:Abnormal uterine bleeding in a patient on maintenance hormonal therapy for breast cancer should raise concern for endometrial abnormalities including rare uterine metastasis from the breast. Hormonal receptor profile changes in metastatic lesions favoring human epidermal growth factor receptor 2 (HER2) overexpression may be involved in the pathogenesis of metastasis to the uterus.

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