The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report

Abnormal uterine bleeding in a patient on maintenance hormonal therapy for breast cancer should raise concern for endometrial abnormalities including rare uterine metastasis from the breast. Hormonal receptor profile changes in metastatic lesions favoring human epidermal growth factor receptor 2 (HE...

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Detalles Bibliográficos
Autores principales: Moey, Melissa Y. Y., Hassan, Omer A., Papageorgiou, Christos N., Schnepp, Stephanie L., Hoff, John T.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2016
Materias:
Case Reports
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054465/
https://www.ncbi.nlm.nih.gov/pubmed/27761241
http://dx.doi.org/10.1002/ccr3.602
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author Moey, Melissa Y. Y.
Hassan, Omer A.
Papageorgiou, Christos N.
Schnepp, Stephanie L.
Hoff, John T.
author_facet Moey, Melissa Y. Y.
Hassan, Omer A.
Papageorgiou, Christos N.
Schnepp, Stephanie L.
Hoff, John T.
author_sort Moey, Melissa Y. Y.
collection PubMed
description Abnormal uterine bleeding in a patient on maintenance hormonal therapy for breast cancer should raise concern for endometrial abnormalities including rare uterine metastasis from the breast. Hormonal receptor profile changes in metastatic lesions favoring human epidermal growth factor receptor 2 (HER2) overexpression may be involved in the pathogenesis of metastasis to the uterus.
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spelling pubmed-50544652016-10-19 The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report Moey, Melissa Y. Y. Hassan, Omer A. Papageorgiou, Christos N. Schnepp, Stephanie L. Hoff, John T. Clin Case Rep Case Reports Abnormal uterine bleeding in a patient on maintenance hormonal therapy for breast cancer should raise concern for endometrial abnormalities including rare uterine metastasis from the breast. Hormonal receptor profile changes in metastatic lesions favoring human epidermal growth factor receptor 2 (HER2) overexpression may be involved in the pathogenesis of metastasis to the uterus. John Wiley and Sons Inc. 2016-08-23 /pmc/articles/PMC5054465/ /pubmed/27761241 http://dx.doi.org/10.1002/ccr3.602 Text en © 2016 The Authors. Clinical Case Reports published by John Wiley & Sons Ltd. This is an open access article under the terms of the Creative Commons Attribution‐NonCommercial‐NoDerivs (http://creativecommons.org/licenses/by-nc-nd/4.0/) License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Case Reports
Moey, Melissa Y. Y.
Hassan, Omer A.
Papageorgiou, Christos N.
Schnepp, Stephanie L.
Hoff, John T.
The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report
title The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report
title_full The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report
title_fullStr The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report
title_full_unstemmed The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report
title_short The potential role of HER2 upregulation in metastatic breast cancer to the uterus: a case report
title_sort potential role of her2 upregulation in metastatic breast cancer to the uterus: a case report
topic Case Reports
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5054465/
https://www.ncbi.nlm.nih.gov/pubmed/27761241
http://dx.doi.org/10.1002/ccr3.602
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